In some cases, however… Interstitial (in-tur-STISH-ul) lung disease describes a large group of disorders, most of which cause progressive scarring of lung tissue. While some anti-inflammatory drugs can damage the lungs, others may help relieve symptoms. INTRODUCTION  Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc) that is often progressive and has a poor prognosis [1-7]. The reason for this relationship is unclear. Background The diagnostic classification “possible idiopathic pulmonary fibrosis (IPF)” is characterised by an inconsistent usual interstitial pneumonia (UIP) pattern on HRCT-scan and a UIP pattern in surgical lung biopsy. An example is the corticosteroid prednisone. Efficacy and safety of intravenous cyclophosphamide pulse therapy with oral prednisolone in the treatment of interstitial lung disease with systemic sclerosis: 4-year follow-up. Prevalence and factors associated with glucocorticoids (GC) use in systemic sclerosis (SSc): a systematic review and meta-analysis of cohort studies and registries. At the end of treatment the low dose group achieved improvement of radiologic lesions and the Warrick index, unlike the high dose group. Objectives: To evaluate the use of intravenous pulse cyclophosphamide combined with low and high doses of prednisone in the treatment of ILD in SS is equally effective. Corticosteroids can have significant side effects. Group B: 10 patients with cyclophosphamide (ev), oral prednisone 10mg daily. However, the treatment is ineffective in one-quarter of patients. Mouthon L, Berezné A, Brauner M, Kambouchner M, Guillevin L, Valeyre D. Presse Med. Diffusing capacity of carbon monoxide (DLCO) decreased by 3.0% (range: 10%‐12%) after treatment in the rituximab group, whereas it increased by 4.5% (range: 30%‐36%) in the control group (p = 0.046). 3 evaluations from interstitial lung disease patients report major effectiveness of Prednisone for interstitial lung disease (33%) 1 evaluation from a interstitial lung disease patient reports moderate effectiveness of Prednisone for interstitial lung disease (11%) Just got out of hospital with superimposed pneumonia. Redd D, Frech TM, Murtaugh MA, Rhiannon J, Zeng QT. Precise distribution and types of tissue damage differ among similar diseases, as does response to treatment with Prednisone. NLM For some people, corticosteroids alone may decrease lung inflammation and cause an improvement in symptoms. Method: An experimental, exploratory and randomized single-blind clinical trial was conducted at … INTRODUCTION — Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without a clear etiology. Pulmonary Hypertension and Interstitial Lung Disease Pulmonary hypertension, or PH, occurs when blood pressure in the lungs becomes elevated, and can be caused by a thickening of the pulmonary artery walls. Clipboard, Search History, and several other advanced features are temporarily unavailable. Rituximab, in combination with CellCept (mycophenolate mofetil), reverses the decline in lung function in people with interstitial lung disease (ILD) associated with scleroderma (SSc) who did not respond to immunosuppressant therapies, a study suggested.. Two patients dropped out of the study. RELATED: Lung Disease Frequently Fatal in Rheumatoid Arthritis.  |  2011 Jun;21(3):296-301. doi: 10.1007/s10165-010-0403-6. 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